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pentobarbital will lower the level or impact of acalabrutinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.pentobarbital will minimize the extent or result of amlodipine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.pentobarbital will minimize the level or impact of nimodipin